Lab Members

Eugene H. Chang, MD FACS

Principal Investigator

Dr. Chang completed his medical school training at Brown University in the Program for Liberal Medical Education (PLME), and proceeded to complete his residency and fellowship at the University of Iowa, which has been ranked in the top ten otolaryngology training programs over the past twenty five years. Dr. Chang became an assistant professor in the Department of Otolaryngology-Head and Neck surgery at the University of Iowa, and since beginning his academic practice has consistently been funded by the National Institute of Health (NIH) for his work in translational sinus research. He moved to the University of Arizona as an Associate Professor in 2014 to lead the Division of Rhinology and Skull base Surgery. He is one of a small number of surgeon-scientists in Otolaryngology that combines an active clinical practice and research expertise to help understand the basic process of sinus disease and develop future therapies and treatments.

Amanda L. Jenkins (Willis), MS

Assistant Scientific Investigator, Lab Manager

Amanda Jenkins is an Arizona native. She graduated with her B.S. from the University of Arizona (2005) with a double major in molecular & cellular biology and biochemistry. During this time she worked in the Dept. of Pharmacology & Toxicology studying mechanisms which effect embryotic heart valve development. Following graduation she accepted a position in the Breast and Ovarian Cancer research unit at TGen (Phoenix, AZ) where she worked for 4 years and obtained her M.S. in molecular & cellular biology through Arizona State University (2009). She then moved to Ann Arbor, MI and worked for 3 years as a researcher and lab manager at the University of Michigan. Her research there focused on mechanisms for how cells invade and migrate through the body using in vitro and chick chorioallantoic membrane model systems. After that Amanda and her husband relocated to Trieste, Italy for 2 years where their daughter was born. Upon their return to Arizona Amanda joined the Chang Lab (February, 2015). Her research focuses on how underlying genetic factors, viral infections, and microbiome composition all interact to drive in the development of chronic sinus disease. When not in the lab she enjoys spending time with her daughter, craft beers, comic books and hiking.


Christopher Le, MD

Assistant Professor

Dr. Chris Le joined the University of Arizona as a Clinical Instructor and Rhinology and Endoscopic Skull Base Surgery Fellow in 2015. He was mentored by Drs. Alexander Chiu and Eugene Chang during fellowship with a clinical and surgical focus in primary and revision endoscopic sinus surgery, endoscopic benign and malignant sinonasal tumor surgery, endoscopic orbital surgery, and endoscopic and open skull base procedures. After fellowship, he stayed on as an Assistant Professor in the Department of Otolaryngology – Head and Neck Surgery. Dr. Le received his undergraduate degree at University of California, Davis. He then obtained his medical degree at the Loma Linda University School of Medicine. He then completed his residency training in Otolaryngology - Head and Neck Surgery at the University of California, Davis Medical Center. Although Dr. Le has a primary clinical interest in rhinology and anterior skull base pathologies, he also has experience in all aspects of Otolaryngology, including maxillofacial trauma. His academic interests are in population health and improving health-care outcomes in Rhinology. He feels privileged and is excited to be a part of the University of Arizona, Otolaryngology - Head and Neck Surgery Department to teach medical students and train residents to become the future generation of Otolaryngologists. Hometown: Yuba City, CA. Outside interests: Anything pertaining to Spider-Man, the Dallas Cowboys or craft beers


Erin G. Romero, BFA

Clinical Research Coordinator

Erin joined the Chang lab after more than ten years working for the University of Utah Department of Pharmacology and Toxicology, in Salt Lake City. Her previous research focused on inhalation toxicology through investigation of mechanisms implicated by exposure to air pollution. Her last several years focused on the effect of inhaled particles on transient receptor potential (TRP) channels, a family of calcium channels that are environmental sensors for temperature as well as known chemical agonists. Working with the upper airway in the Chang lab is a perfect opportunity to gain experience in a new area and apply her previous knowledge. Erin works to find balance between her research career and her other interests. With a B.F.A. in Modern Dance, Erin also has nine years of experience as a certified Pilates instructor teaching in several locations including Wellington, New Zealand, Santa Barbara, CA and Salt Lake City, UT.


Jaeden T. Calton

Student Research Assistant

Jaeden Calton born in Sacramento, California is currently an undergraduate student at the University of Arizona who is majoring in Physiology. Showing large interests in several branches of medicine, Jaeden hopes to one day attend medical school. His current position includes lab procedures focusing on human rhinovirus and CFTR mutation. In his spare time, Jaeden enjoys fly fishing and watching sports games with his friends.


George Noutsios, PhD

Postdoctoral Research Associate III

George Noutsios was born and raised in Thessaloniki, Greece, has a BSc in Chemistry (2004), a MSc in Biochemistry (2006) and a PhD in Biochemistry/Molecular Biology (2009) from Aristotle University of Thessaloniki. His dissertation focused on immobilization of antigenic biomolecules in bio-polymeric substrates for detection and diagnosis of endemic Brucella melitensis biotypes. In 2011 he came to USA to pursue his career in lung diseases research. During his postdoc at Penn State Hershey Medical Center (2011-2016) he studied the role of cis-acting elements and trans-acting factors on splicing and translation of the pulmonary surfactant protein A, and he identified 14-3-3 isoforms and microRNAs as potential therapeutic regulatory molecules in lung diseases. He recently joined the Chang Lab and he is involved in a collaborate effort to unveil the primary mechanisms of chronic sinusitis in upper airway diseases utilizing in vivo and in vitro air-liquid interface models. In his spare time, George enjoys traveling, working out at the gym, trying good food and craft beer.


Dana Zack, BS

Research Lab Technician

Dana Zack was born and raised in Phoenix, Arizona. She attended college at the University of Arizona, from which she graduated in 2016 with a B.S. in Biology (biomedical focus), as well as a minor in Ecology and Evolutionary Biology. Her research interests in the Chang lab include exploring the sinus microbiome and potential genetic risk factors for chronic sinusitis. In addition to her research endeavors, she is a medical scribe at Banner UMC for the Department of Otolaryngology. A few of her non-professional interests include ultimate frisbee, crafting, hiking/camping, and downhill skiing.​


Alexander Kim, BSE

Research Lab Technician

Alexander Kim was born and raised in Honolulu, Hawaii and moved to Tucson, Arizona in 2007. He attended Arizona State University, where he graduated in 2016 with a BSE in Mechanical Engineering. His previous research experience at Arizona State involved the development of a protocol that uses silver nitrate ink for 3D nanofabrication. His current research interests in the Chang lab involve studying the effects of maxillary sinus balloon dilation on patient sinus microbiomes. In addition to his research, Alexander Kim also assists the Chang lab with CDHR3 and CTFR genotyping. When he’s not in lab, Alex can be found playing with his dog, biking, drinking craft beers, or sleeping.