Publications

2021

Zack, D. E., D. A. Stern, A. L. Willis, A. S. Kim, C. J. Mansfield, D. R. Reed, S. G. Brooks, N. D. Adappa, J. N. Palmer, N. A. Cohen, et al., "The GSDMB rs7216389 SNP is associated with chronic rhinosinusitis in a multi-institutional cohort.", Int Forum Allergy Rhinol, 2021 Jun 02. PMID: 34076350
C Bailey, E., J. S. Grauer, P. G. Chen, S. V. Rangarajan, Y. Chan, M. A. Tewfik, M. J. Marino, M. Torabi, C. H. Le, and E. H. Chang, "Development of a self-directed sinonasal surgical anatomy video curriculum: Phase 1 validation.", Int Forum Allergy Rhinol, 2021 May 21. PMID: 34021535
Orlandi, R. R., T. T. Kingdom, T. L. Smith, B. Bleier, A. DeConde, A. U. Luong, D. M. Poetker, Z. Soler, K. C. Welch, S. K. Wise, et al., "International consensus statement on allergy and rhinology: rhinosinusitis 2021.", Int Forum Allergy Rhinol, vol. 11, issue 3, pp. 213-739, 2021 Mar. PMID: 33236525

2020

Vaidyanathan, S., A. A. Salahudeen, Z. M. Sellers, D. T. Bravo, S. S. Choi, A. Batish, W. Le, R. Baik, S. de la O, M. P. Kaushik, et al., "High-Efficiency, Selection-free Gene Repair in Airway Stem Cells from Cystic Fibrosis Patients Rescues CFTR Function in Differentiated Epithelia.", Cell Stem Cell, vol. 26, issue 2, pp. 161-171.e4, 2020 02 06. PMID: 31839569
Richards, J. P., A. J. Done, S. R. Barber, S. Jain, Y-J. Son, and E. H. Chang, "Virtual coach: the next tool in functional endoscopic sinus surgery education.", Int Forum Allergy Rhinol, vol. 10, issue 1, pp. 97-102, 2020 01. PMID: 31834672
Chang, E. H., "How our specialty can contribute and benefit from COVID-19 research.", Int Forum Allergy Rhinol, vol. 10, issue 12, pp. 1274-1275, 2020 12. PMCID: PMC7677857  PMID: 33044801
Willis, A. L., J. B. Calton, J. Calton, A. S. Kim, R. Lee, E. Torabzadeh, D. D. Billheimer, C. H. Le, F. D. Martinez, and E. H. Chang, "RV-C infections result in greater clinical symptoms and epithelial responses compared to RV-A infections in patients with CRS.", Allergy, vol. 75, issue 12, pp. 3264-3267, 2020 12. PMID: 32510622
Chang, E. H., A. L. Willis, C. E. Romanoski, D. A. Cusanovich, N. Pouladi, J. Li, Y. A. Lussier, and F. D. Martinez, "Rhinovirus Infections in Individuals with Asthma Increase ACE2 Expression and Cytokine Pathways Implicated in COVID-19.", Am J Respir Crit Care Med, vol. 202, issue 5, pp. 753-755, 2020 09 01. PMCID: PMC7462393  PMID: 32649217
Kato, K., E. H. Chang, Y. Chen, W. Lu, M. M. Kim, M. Niihori, L. Hecker, and K. Chul Kim, "MUC1 contributes to goblet cell metaplasia and MUC5AC expression in response to cigarette smoke in vivo.", Am J Physiol Lung Cell Mol Physiol, vol. 319, issue 1, pp. L82-L90, 2020 07 01. PMCID: PMC7468848  PMID: 32401676
Mitts, K. B., and E. H. Chang, "Genetics of chronic rhinosinusitis.", J Allergy Clin Immunol, vol. 145, issue 3, pp. 777-779, 2020 03. PMID: 32007429

2019

Kim, A. S., A. L. Willis, D. Laubitz, S. Sharma, B. H. Song, A. G. Chiu, C. H. Le, and E. H. Chang, "The effect of maxillary sinus antrostomy size on the sinus microbiome.", Int Forum Allergy Rhinol, vol. 9, issue 1, pp. 30-38, 2019 Jan. PMID: 30358937
Kato, K., B. H. Song, C. L. Howe, and E. H. Chang, "A Comprehensive Systematic Review of the Association Between Airway Mucins and Chronic Rhinosinusitis.", Am J Rhinol Allergy, vol. 33, issue 4, pp. 433-448, 2019 Jul. PMID: 30892914
Chang, E. H., "The role of surfactant protein-A in sinusitis.", Curr Opin Allergy Clin Immunol, vol. 19, issue 1, pp. 26-29, 2019 02. PMID: 30507715

2018

Sharma, S., H. McCrary, E. Romero, A. Kim, E. Chang, and C. H. Le, "A prospective, randomized, single-blinded trial for improving health outcomes in rhinology by the use of personalized video recordings.", Int Forum Allergy Rhinol, vol. 8, issue 12, pp. 1406-1411, 2018 12. PMID: 30221851
Barber, S. R., S. Jain, Y-J. Son, and E. H. Chang, "Virtual Functional Endoscopic Sinus Surgery Simulation with 3D-Printed Models for Mixed-Reality Nasal Endoscopy.", Otolaryngol Head Neck Surg, vol. 159, issue 5, pp. 933-937, 2018 11. PMID: 30200812
Christensen, D. N., Z. G. Franks, H. C. McCrary, A. A. Saleh, and E. H. Chang, "A Systematic Review of the Association between Cigarette Smoke Exposure and Chronic Rhinosinusitis.", Otolaryngol Head Neck Surg, vol. 158, issue 5, pp. 801-816, 2018 05. PMID: 29460678
Chang, E. H., D. A. Stern, A. L. Willis, S. Guerra, A. L. Wright, and F. D. Martinez, "Early life risk factors for chronic sinusitis: a longitudinal birth cohort study.", J Allergy Clin Immunol, 2018 Jan 17. PMID: 29355680

2017

Noutsios, G. T., A. L. Willis, J. G. Ledford, and E. H. Chang, "Novel role of surfactant protein A in bacterial sinusitis.", Int Forum Allergy Rhinol, vol. 7, issue 9, pp. 897-903, 2017 Sep. PMCID: PMC5783157  PMID: 28727907
Levy, J. M., S. Shintani Smith, R. Varshney, E. H. Chang, V. R. Ramakrishnan, J. Y. Ting, and B. S. Bleier, "Trends in sinusitis research: a systematic review of extramural funding.", Int Forum Allergy Rhinol, vol. 7, issue 11, pp. 1104-1107, 2017 11. PMID: 28985031
Palejwala, S. K., S. Sharma, C. H. Le, E. Chang, and M. Lemole, "Complications of Advanced Kadish Stage Esthesioneuroblastoma: Single Institution Experience and Literature Review.", Cureus, vol. 9, issue 5, pp. e1245, 2017 May 12. PMCID: PMC5467981  PMID: 28620574
Calton, J. B., P. C. Koripella, A. L. Willis, C. H. Le, A. G. Chiu, and E. H. Chang, "Paranasal sinus size is decreased in CFTR heterozygotes with chronic rhinosinusitis.", Int Forum Allergy Rhinol, vol. 7, issue 3, pp. 256-260, 2017 Mar. PMID: 27860385
Palejwala, S. K., S. Sharma, C. H. Le, E. Chang, A. B. Erman, and M. G Lemole, "Complex Skull Base Reconstructions in Kadish D Esthesioneuroblastoma: Case Report.", J Neurol Surg Rep, vol. 78, issue 2, pp. e86-e92, 2017 Apr. PMCID: PMC5418125  PMID: 28480156

2016

Barry, J. Y., H. C. McCrary, S. Kent, A. A. Saleh, E. H. Chang, and A. G. Chiu, "The Triple Aim and its implications on the management of chronic rhinosinusitis.", Am J Rhinol Allergy, vol. 30, issue 5, pp. 344-50, 2016 Sep. PMID: 27657900
Le, C., H. C. McCrary, and E. Chang, "Cystic Fibrosis Sinusitis.", Adv Otorhinolaryngol, vol. 79, pp. 29-37, 2016. PMID: 27466844
Barry, J. Y., C. H. Le, J. Baumann, L. Skinker, A. G. Chiu, and E. H. Chang, "Endoscopic resection of maxillary sinus keratocystic odontogenic tumors.", Laryngoscope, 2016 Mar 12. PMID: 26972016
Willis, A. L., J. B. Calton, T. F. Carr, A. G. Chiu, and E. H. Chang, "Dead or alive: Deoxyribonuclease I sensitive bacteria and implications for the sinus microbiome.", Am J Rhinol Allergy, vol. 30, issue 2, pp. 94-8, 2016 Mar. PMCID: PMC4782214  PMID: 26715059
Ahmad, S., C. H. Le, A. G. Chiu, and E. H. Chang, "Incidence of intracranial radiation necrosis following postoperative radiation therapy for sinonasal malignancies.", Laryngoscope, 2016 Jun 14. PMID: 27296477
Carr, T. F., J. L. Hill, A. Chiu, and E. H. Chang, "Alteration in Bacterial Culture After Treatment With Topical Mupirocin for Recalcitrant Chronic Rhinosinusitis.", JAMA Otolaryngol Head Neck Surg, vol. 142, issue 2, pp. 138-42, 2016 Feb 1. PMID: 26720201
Chang, E. H., A. L. Willis, H. C. McCrary, G. T. Noutsios, C. H. Le, A. G. Chiu, C. J. Mansfield, D. R. Reed, S. G. Brooks, N. D. Adappa, et al., "Association between the CDHR3 rs6967330 risk allele and chronic rhinosinusitis.", J Allergy Clin Immunol, 2016 Dec 03. PMID: 27923563
Faucett, E. A., B. T. Larsen, R. Khan, A. G. Chiu, and E. H. Chang, "A Diagnostic Dilemma: Multiple Primary Intracranial Tumors Without Vestibular Schwannomas.", Ann Otol Rhinol Laryngol, vol. 125, issue 11, pp. 938-942, 2016 Nov. PMID: 27553596

2015

Chang, E. H., and J. Zabner, "Precision Genomic Medicine in Cystic Fibrosis.", Clin Transl Sci, vol. 8, issue 5, pp. 606-10, 2015 Oct. PMCID: PMC4626267  PMID: 26073768
Chang, E. H., X. Xiao Tang, V. S. Shah, J. L. Launspach, S. E. Ernst, B. Hilkin, P. H. Karp, M. H. Abou Alaiwa, S. M. Graham, D. B. Hornick, et al., "Medical reversal of chronic sinusitis in a cystic fibrosis patient with ivacaftor.", Int Forum Allergy Rhinol, vol. 5, issue 2, pp. 178-81, 2015 Feb. PMCID: PMC4310814  PMID: 25363320
Potter, N. J., S. M. Graham, E. H. Chang, and J. D. W. Greenlee, "Bioabsorbable plate cranial base reconstruction.", Laryngoscope, vol. 125, issue 6, pp. 1313-5, 2015 Jun. PMID: 25363091

2014

Kopelovich, J. C., M. S. Baker, A. Potash, L. Desai, R. C. Allen, and E. H. Chang, "The hybrid lid crease approach to address lateral frontal sinus disease with orbital extension.", Ann Otol Rhinol Laryngol, vol. 123, issue 12, pp. 826-30, 2014 Dec. PMCID: PMC4301847  PMID: 24944279
Chang, E. H., "New insights into the pathogenesis of cystic fibrosis sinusitis.", Int Forum Allergy Rhinol, vol. 4, issue 2, pp. 132-7, 2014 Feb. PMCID: PMC3946531  PMID: 24282147

2013

Fletcher, A., J. Choi, M. Awadalla, A. E. Potash, T. J. Wallen, S. Fletcher, and E. H. Chang, "The effect of geniglossal advancement on airway flow using a computational flow dynamics model.", Laryngoscope, vol. 123, issue 12, pp. 3227-32, 2013 Dec. PMCID: PMC3783525  PMID: 23686418
Stoltz, D. A., T. Rokhlina, S. E. Ernst, A. A. Pezzulo, L. S. Ostedgaard, P. H. Karp, M. S. Samuel, L. R. Reznikov, M. V. Rector, N. D. Gansemer, et al., "Intestinal CFTR expression alleviates meconium ileus in cystic fibrosis pigs.", J Clin Invest, vol. 123, issue 6, pp. 2685-93, 2013 Jun. PMCID: PMC3668832  PMID: 23676501
Potash, A. E., T. J. Wallen, P. H. Karp, S. Ernst, T. O. Moninger, N. D. Gansemer, D. A. Stoltz, J. Zabner, and E. H. Chang, "Adenoviral gene transfer corrects the ion transport defect in the sinus epithelia of a porcine CF model.", Mol Ther, vol. 21, issue 5, pp. 947-53, 2013 May. PMCID: PMC3666638  PMID: 23511247

2012

Dlouhy, B. J., K. Madhavan, J. D. Clinger, A. Reddy, J. D. Dawson, E. K. O'Brien, E. Chang, S. M. Graham, and J. D. W. Greenlee, "Elevated body mass index and risk of postoperative CSF leak following transsphenoidal surgery.", J Neurosurg, vol. 116, issue 6, pp. 1311-7, 2012 Jun. PMCID: PMC3449304  PMID: 22443502
Sinn, P. L., A. L. Cooney, M. Oakland, D. E. Dylla, T. J. Wallen, A. A. Pezzulo, E. H. Chang, and P. B. McCray, "Lentiviral vector gene transfer to porcine airways.", Mol Ther Nucleic Acids, vol. 1, pp. e56, 2012. PMCID: PMC3511674  PMID: 23187455
Chang, E. H., A. A. Pezzulo, D. K. Meyerholz, A. E. Potash, T. J. Wallen, L. R. Reznikov, J. C. Sieren, P. H. Karp, S. Ernst, T. O. Moninger, et al., "Sinus hypoplasia precedes sinus infection in a porcine model of cystic fibrosis.", Laryngoscope, vol. 122, issue 9, pp. 1898-905, 2012 Sep. PMCID: PMC3449319  PMID: 22711071
Lacruz, R. S., C. E. Smith, P. Moffatt, E. H. Chang, T. G. Bromage, P. Bringas, A. Nanci, S. K. Baniwal, J. Zabner, M. J. Welsh, et al., "Requirements for ion and solute transport, and pH regulation during enamel maturation.", J Cell Physiol, vol. 227, issue 4, pp. 1776-85, 2012 Apr. PMCID: PMC3373187  PMID: 21732355

2011

Chang, E. H., R. S. Lacruz, T. G. Bromage, P. Bringas, M. J. Welsh, J. Zabner, and M. L. Paine, "Enamel pathology resulting from loss of function in the cystic fibrosis transmembrane conductance regulator in a porcine animal model.", Cells Tissues Organs, vol. 194, issue 2-4, pp. 249-54, 2011. PMCID: PMC3178086  PMID: 21525720
Chang, E. H., A. A. Pezzulo, and J. Zabner, "Do cell junction protein mutations cause an airway phenotype in mice or humans?", Am J Respir Cell Mol Biol, vol. 45, issue 2, pp. 202-20, 2011 Aug. PMCID: PMC3175552  PMID: 21297078

2010

Chang, E. H., J. H. Lee, and J. Zabner, "Tryptase does not alter transepithelial conductance or paracellular permeability in human airway epithelial cells.", Am J Rhinol Allergy, vol. 24, issue 2, pp. 126-8, 2010 Mar-Apr. PMID: 20338110
Stoltz, D. A., D. K. Meyerholz, A. A. Pezzulo, S. Ramachandran, M. P. Rogan, G. J. Davis, R. A. Hanfland, C. Wohlford-Lenane, C. L. Dohrn, J. A. Bartlett, et al., "Cystic fibrosis pigs develop lung disease and exhibit defective bacterial eradication at birth.", Sci Transl Med, vol. 2, issue 29, pp. 29ra31, 2010 Apr 28. PMCID: PMC2889616  PMID: 20427821

2009

Chang, E. H., T. E. Lobe, and S. K. Wright, "Our initial experience of the transaxillary totally endoscopic approach for hemithyroidectomy.", Otolaryngol Head Neck Surg, vol. 141, issue 3, pp. 335-9, 2009 Sep. PMID: 19716009

2008

Chang, E. Hanyoung, and G. S. Hamilton, "Novel technique for peritonsillar abscess drainage.", Ann Otol Rhinol Laryngol, vol. 117, issue 9, pp. 637-40, 2008 Sep. PMID: 18834063

2005

Vore, A. P., E. H. Chang, J. E. Hoppe, M. G. Butler, S. Forrester, M. C. Schneider, L. L. H. Smith, D. W. Burke, C. A. Campbell, and R. J. H. Smith, "Deletion of and novel missense mutation in POU3F4 in 2 families segregating X-linked nonsyndromic deafness.", Arch Otolaryngol Head Neck Surg, vol. 131, issue 12, pp. 1057-63, 2005 Dec. PMID: 16365218

2004

Chang, E. H., M. Menezes, N. C. Meyer, R. A. Cucci, V. S. Vervoort, C. E. Schwartz, and R. J. H. Smith, "Branchio-oto-renal syndrome: the mutation spectrum in EYA1 and its phenotypic consequences.", Hum Mutat, vol. 23, issue 6, pp. 582-9, 2004 Jun. PMID: 15146463
Ruf, R. G., P-X. Xu, D. Silvius, E. A. Otto, F. Beekmann, U. T. Muerb, S. Kumar, T. J. Neuhaus, M. J. Kemper, R. M. Raymond, et al., "SIX1 mutations cause branchio-oto-renal syndrome by disruption of EYA1-SIX1-DNA complexes.", Proc Natl Acad Sci U S A, vol. 101, issue 21, pp. 8090-5, 2004 May 25. PMCID: PMC419562  PMID: 15141091
Husein, M., E. Chang, B. Cable, M. Karnell, L. Hynds Karnell, and J. W. Canady, "Outcomes for children with submucous cleft palate and velopharyngeal insufficiency.", J Otolaryngol, vol. 33, issue 4, pp. 222-6, 2004 Aug. PMID: 15903202

2003

Chang, E. H., G. Van Camp, and R. J. H. Smith, "The role of connexins in human disease.", Ear Hear, vol. 24, issue 4, pp. 314-23, 2003 Aug. PMID: 12923422

2001

Lee, M. H., Z. Qu, G. A. Fishbein, S. T. Lamp, E. H. Chang, T. Ohara, O. Voroshilovsky, J. R. Kil, A. R. Hamzei, N. C. Wang, et al., "Patterns of wave break during ventricular fibrillation in isolated swine right ventricle.", Am J Physiol Heart Circ Physiol, vol. 281, issue 1, pp. H253-65, 2001 Jul. PMID: 11406492