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WELCOME TO THE CHANG LAB
The main focus of the Chang Laboratory is to determine the mechanisms underlying chronic rhinosinusitis (CRS); a complex heterogeneous disorder affecting 15 million people in the United States with costs exceeding 11 billion dollars per year. Dr. Chang is a physician-scientist who provides medical and surgical care for those with upper airway (nasal, sinus, and skull base) disorders. Currently our therapies include medications and surgeries that treat the symptoms of disease. Our goal is to utilize modern molecular techniques to identify the primary cause and translate these findings to improve therapies for our patients.
Our research interests include:
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Rhinovirus and unified airway disease: Rhinovirus is implicated in chronic rhinosinusitis, asthma, and COPD exacerbations. Our goal is to identify the genome-virome epithelial response in airway epithelia.
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CFTR-related sinus disease: identify the mechanism of disease for those with cystic fibrosis (two CFTR mutations) and CF carriers (single CFTR mutation).
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Surgical simulation for functional endoscopic sinus surgery (FESS).
Discover more here.
NEWS AND UPDATES
Jacob Herbert presents his poster at the 2024 UBRP Conference.
Ibrahim Ramadan presents his poster at the 2024 UBRP Conference.
Dr. Chang’s research highlighted in JACI as an Editor’s choice article – Rhinovirus-induced endotypes distinguish a childhood persistent wheeze-phenotype in adult asthmatic subjects
Congratulations to Dr. Eugene Chang and Nirushan Narendran for presenting their clinical studies at the 2022 AAAAI annual meeting!
Congratulations to our undergraduate Sophia Volpe for presenting her research at the University of Arizona Chemistry and Biochemistry poster fair and winning the Viewer's Pick award!
Lab members and their families celebrate the start of a new school year with pizza at Anello
Lab members and their families celebrate the start of a new school year with pizza at Anello
Nirushan Narendran presents his research at the American Rhinologic Society 2022
Dr. Eric Bailey, a graduate of the Neurorhinology fellowship program, presents his work at the American Rhinologic Society 2022