Chang E, Pouladi N, Guerra S, et al. Epithelial cell responses to rhinovirus identify an early-life-onset asthma phenotype in adults. The Journal of allergy and clinical immunology. 2022;150(3):604-611. doi:10.1016/j.jaci.2022.03.020
PMID: 35367470



Beswick D, Hwang P, Adappa N, et al. Surgical approach is associated with complication rate in sinonasal malignancy: A multicenter study. International forum of allergy & rhinology. 2021;11(12):1617-1625. doi:10.1002/alr.22833
PMID: 34176231


Orlandi R, Kingdom T, Smith T, et al. International consensus statement on allergy and rhinology: rhinosinusitis 2021. International forum of allergy & rhinology. 2021;11(3):213-739. doi:10.1002/alr.22741
PMID: 33236525


Bailey E, Grauer J, Chen P, et al. Development of a self-directed sinonasal surgical anatomy video curriculum: Phase 1 validation. International forum of allergy & rhinology. 2021;11(11):1570-1576. doi:10.1002/alr.22814
PMID: 34021535


Zack D, Stern D, Willis A, et al. The GSDMB rs7216389 SNP is associated with chronic rhinosinusitis in a multi-institutional cohort. International forum of allergy & rhinology. 2021;11(12):1647-1653. doi:10.1002/alr.22824
PMID: 34076350



Kato K, Chang E, Chen Y, et al. MUC1 contributes to goblet cell metaplasia and MUC5AC expression in response to cigarette smoke in vivo. American journal of physiology. Lung cellular and molecular physiology. 2020;319(1):L82-L90. doi:10.1152/ajplung.00049.2019
PMID: 32401676


Richards J, Done A, Barber S, Jain S, Son Y-J, Chang E. Virtual coach: the next tool in functional endoscopic sinus surgery education. International forum of allergy & rhinology. 2020;10(1):97-102. doi:10.1002/alr.22452
PMID: 31834672


Vaidyanathan S, Salahudeen A, Sellers Z, et al. High-Efficiency, Selection-free Gene Repair in Airway Stem Cells from Cystic Fibrosis Patients Rescues CFTR Function in Differentiated Epithelia. Cell stem cell. 2020;26(2):161-171.e4. doi:10.1016/j.stem.2019.11.002
PMID: 31839569


Mitts K, Chang E. Genetics of chronic rhinosinusitis. The Journal of allergy and clinical immunology. 2020;145(3):777-779. doi:10.1016/j.jaci.2020.01.029
PMID: 32007429


Chang E. How our specialty can contribute and benefit from COVID-19 research. International forum of allergy & rhinology. 2020;10(12):1274-1275. doi:10.1002/alr.22719
PMID: 33044801


Willis A, Calton J, Calton J, et al. RV-C infections result in greater clinical symptoms and epithelial responses compared to RV-A infections in patients with CRS. Allergy. 2020;75(12):3264-3267. doi:10.1111/all.14435
PMID: 32510622


Jain S, Lee S, Barber SR, Chang EH, Son Y-J. Virtual reality based hybrid simulation for functional endoscopic sinus surgery. IISE Transactions on Healthcare Systems Engineering. 2020. doi:10.1080/24725579.2019.1692263
Chang E, Willis A, Romanoski C, et al. Rhinovirus Infections in Individuals with Asthma Increase ACE2 Expression and Cytokine Pathways Implicated in COVID-19. American journal of respiratory and critical care medicine. 2020;202(5):753-755. doi:10.1164/rccm.202004-1343LE
PMID: 32649217



Vaidyanathan S, Salahudeen AA, Sellers ZM, et al. Highly Efficient Repair of the ΔF508 Mutation in Airway Stem Cells of Cystic Fibrosis Patients with Functional Rescue of the Differentiated Epithelia. bioRxiv. 2019. doi:
Kim A, Willis A, Laubitz D, et al. The effect of maxillary sinus antrostomy size on the sinus microbiome. International forum of allergy & rhinology. 2019;9(1):30-38. doi:10.1002/alr.22224
PMID: 30358937


Chang E. The role of surfactant protein-A in sinusitis. Current opinion in allergy and clinical immunology. 2019;19(1):26-29. doi:10.1097/ACI.0000000000000500
PMID: 30507715


Kato K, Song B, Howe C, Chang E. A Comprehensive Systematic Review of the Association Between Airway Mucins and Chronic Rhinosinusitis. American journal of rhinology & allergy. 2019;33(4):433-448. doi:10.1177/1945892419837042
PMID: 30892914



Barber S, Jain S, Son Y-J, Chang E. Virtual Functional Endoscopic Sinus Surgery Simulation with 3D-Printed Models for Mixed-Reality Nasal Endoscopy. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery. 2018;159(5):933-937. doi:10.1177/0194599818797586
PMID: 30200812


Sharma S, McCrary H, Romero E, Kim A, Chang E, Le C. A prospective, randomized, single-blinded trial for improving health outcomes in rhinology by the use of personalized video recordings. International forum of allergy & rhinology. 2018;8(12):1406-1411. doi:10.1002/alr.22145
PMID: 30221851


Chang E, Stern D, Willis A, Guerra S, Wright A, Martinez F. Early life risk factors for chronic sinusitis: A longitudinal birth cohort study. The Journal of allergy and clinical immunology. 2018;141(4):1291-1297.e2. doi:10.1016/j.jaci.2017.11.052
PMID: 29355680


Christensen D, Franks Z, McCrary H, Saleh A, Chang E. A Systematic Review of the Association between Cigarette Smoke Exposure and Chronic Rhinosinusitis. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery. 2018;158(5):801-816. doi:10.1177/0194599818757697
PMID: 29460678



Noutsios G, Willis A, Ledford J, Chang E. Novel role of surfactant protein A in bacterial sinusitis. International forum of allergy & rhinology. 2017;7(9):897-903. doi:10.1002/alr.21985
PMID: 28727907


Palejwala S, Sharma S, Le C, Chang E, Erman A, Lemole M. Complex Skull Base Reconstructions in Kadish D Esthesioneuroblastoma: Case Report. Journal of neurological surgery reports. 2017;78(2):e86-e92. doi:10.1055/s-0037-1601877
PMID: 28480156


Calton J, Koripella P, Willis A, Le C, Chiu A, Chang E. Paranasal sinus size is decreased in CFTR heterozygotes with chronic rhinosinusitis. International forum of allergy & rhinology. 2017;7(3):256-260. doi:10.1002/alr.21874
PMID: 27860385


Palejwala S, Sharma S, Le C, Chang E, Lemole M. Complications of Advanced Kadish Stage Esthesioneuroblastoma: Single Institution Experience and Literature Review. Cureus. 2017;9(5):e1245. doi:10.7759/cureus.1245
PMID: 28620574


Chang E, Willis A, McCrary H, et al. Association between the CDHR3 rs6967330 risk allele and chronic rhinosinusitis. The Journal of allergy and clinical immunology. 2017;139(6):1990-1992.e2. doi:10.1016/j.jaci.2016.10.027
PMID: 27923563


Levy J, Smith S, Varshney R, et al. Trends in sinusitis research: a systematic review of extramural funding. International forum of allergy & rhinology. 2017;7(11):1104-1107. doi:10.1002/alr.22015
PMID: 28985031



Barry J, Le C, Baumann J, Skinker L, Chiu A, Chang E. Endoscopic resection of maxillary sinus keratocystic odontogenic tumors. The Laryngoscope. 2016;126(10):2216-9. doi:10.1002/lary.25920
PMID: 26972016


Willis A, Calton J, Carr T, Chiu A, Chang E. Dead or alive: Deoxyribonuclease I sensitive bacteria and implications for the sinus microbiome. American journal of rhinology & allergy. 2016;30(2):94-8. doi:10.2500/ajra.2016.30.4278
PMID: 26715059


Ahmad S, Le C, Chiu A, Chang E. Incidence of intracranial radiation necrosis following postoperative radiation therapy for sinonasal malignancies. The Laryngoscope. 2016;126(11):2445-2450. doi:10.1002/lary.26106
PMID: 27296477


Carr T, Hill J, Chiu A, Chang E. Alteration in Bacterial Culture After Treatment With Topical Mupirocin for Recalcitrant Chronic Rhinosinusitis. JAMA otolaryngology-- head & neck surgery. 2016;142(2):138-42. doi:10.1001/jamaoto.2015.3059
PMID: 26720201


Faucett E, Larsen B, Khan R, Chiu A, Chang E. A Diagnostic Dilemma: Multiple Primary Intracranial Tumors Without Vestibular Schwannomas. The Annals of otology, rhinology, and laryngology. 2016;125(11):938-942.
PMID: 27553596


Barry J, McCrary H, Kent S, Saleh A, Chang E, Chiu A. The Triple Aim and its implications on the management of chronic rhinosinusitis. American journal of rhinology & allergy. 2016;30(5):344-50. doi:10.2500/ajra.2016.30.4348
PMID: 27657900


Le C, McCrary H, Chang E. Cystic Fibrosis Sinusitis. Advances in oto-rhino-laryngology. 2016;79:29-37. doi:10.1159/000444959
PMID: 27466844



Chang E, Zabner J. Precision Genomic Medicine in Cystic Fibrosis. Clinical and translational science. 2015;8(5):606-10. doi:10.1111/cts.12292
PMID: 26073768


Potter N, Graham S, Chang E, Greenlee J. Bioabsorbable plate cranial base reconstruction. The Laryngoscope. 2015;125(6):1313-5. doi:10.1002/lary.24991
PMID: 25363091



Chang E. New insights into the pathogenesis of cystic fibrosis sinusitis. International forum of allergy & rhinology. 2014;4(2):132-7. doi:10.1002/alr.21252
PMID: 24282147


Kopelovich J, Baker M, Potash A, Desai L, Allen R, Chang E. The hybrid lid crease approach to address lateral frontal sinus disease with orbital extension. The Annals of otology, rhinology, and laryngology. 2014;123(12):826-30. doi:10.1177/0003489414538767
PMID: 24944279



Fletcher A, Choi J, Awadalla M, et al. The effect of geniglossal advancement on airway flow using a computational flow dynamics model. The Laryngoscope. 2013;123(12):3227-32. doi:10.1002/lary.24203
PMID: 23686418


Stoltz D, Rokhlina T, Ernst S, et al. Intestinal CFTR expression alleviates meconium ileus in cystic fibrosis pigs. The Journal of clinical investigation. 2013;123(6):2685-93. doi:10.1172/JCI68867
PMID: 23676501


Potash A, Wallen T, Karp P, et al. Adenoviral gene transfer corrects the ion transport defect in the sinus epithelia of a porcine CF model. Molecular therapy : the journal of the American Society of Gene Therapy. 2013;21(5):947-53. doi:10.1038/mt.2013.49
PMID: 23511247



Sinn P, Cooney A, Oakland M, et al. Lentiviral vector gene transfer to porcine airways. Molecular therapy. Nucleic acids. 2012;1:e56. doi:10.1038/mtna.2012.47
PMID: 23187455


Dlouhy B, Madhavan K, Clinger J, et al. Elevated body mass index and risk of postoperative CSF leak following transsphenoidal surgery. Journal of neurosurgery. 2012;116(6):1311-7. doi:10.3171/2012.2.JNS111837
PMID: 22443502


Lacruz R, Smith C, Moffatt P, et al. Requirements for ion and solute transport, and pH regulation during enamel maturation. Journal of cellular physiology. 2012;227(4):1776-85. doi:10.1002/jcp.22911
PMID: 21732355


Chang E, Pezzulo A, Meyerholz D, et al. Sinus hypoplasia precedes sinus infection in a porcine model of cystic fibrosis. The Laryngoscope. 2012;122(9):1898-905. doi:10.1002/lary.23392
PMID: 22711071



Chang E, Lacruz R, Bromage T, et al. Enamel pathology resulting from loss of function in the cystic fibrosis transmembrane conductance regulator in a porcine animal model. Cells, tissues, organs. 2011;194(2-4):249-54. doi:10.1159/000324248
PMID: 21525720


Chang E, Pezzulo A, Zabner J. Do cell junction protein mutations cause an airway phenotype in mice or humans? American journal of respiratory cell and molecular biology. 2011;45(2):202-20. doi:10.1165/rcmb.2010-0498TR
PMID: 21297078



Stoltz D, Meyerholz D, Pezzulo A, et al. Cystic fibrosis pigs develop lung disease and exhibit defective bacterial eradication at birth. Science translational medicine. 2010;2(29):29ra31. doi:10.1126/scitranslmed.3000928
PMID: 20427821


Chang E, Lee J, Zabner J. Tryptase does not alter transepithelial conductance or paracellular permeability in human airway epithelial cells. American journal of rhinology & allergy. 2010;24(2):126-8. doi:10.2500/ajra.2010.24.3442
PMID: 20338110



Chang E, Lobe T, Wright S. Our initial experience of the transaxillary totally endoscopic approach for hemithyroidectomy. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery. 2009;141(3):335-9. doi:10.1016/j.otohns.2009.05.026
PMID: 19716009



Chang E, Hamilton G. Novel technique for peritonsillar abscess drainage. The Annals of otology, rhinology, and laryngology. 2008;117(9):637-40.
PMID: 18834063



Vore A, Chang E, Hoppe J, et al. Deletion of and novel missense mutation in POU3F4 in 2 families segregating X-linked nonsyndromic deafness. Archives of otolaryngology--head & neck surgery. 2005;131(12):1057-63.
PMID: 16365218



Ruf R, Xu P-X, Silvius D, et al. SIX1 mutations cause branchio-oto-renal syndrome by disruption of EYA1-SIX1-DNA complexes. Proceedings of the National Academy of Sciences of the United States of America. 2004;101(21):8090-5.
PMID: 15141091


Chang E, Menezes M, Meyer N, et al. Branchio-oto-renal syndrome: the mutation spectrum in EYA1 and its phenotypic consequences. Human mutation. 2004;23(6):582-9.
PMID: 15146463


Husein M, Chang E, Cable B, Karnell M, Karnell L, Canady J. Outcomes for children with submucous cleft palate and velopharyngeal insufficiency. The Journal of otolaryngology. 2004;33(4):222-6.
PMID: 15903202



Chang E, Van Camp G, Smith R. The role of connexins in human disease. Ear and hearing. 2003;24(4):314-23.
PMID: 12923422



Lee M, Qu Z, Fishbein G, et al. Patterns of wave break during ventricular fibrillation in isolated swine right ventricle. American journal of physiology. Heart and circulatory physiology. 2001;281(1):H253-65.
PMID: 11406492